A systematic review of air quality levels and SLE rates among developed and developing countries
Abstract
Abstract:
Research on the impact of air pollution on Systemic Lupus Erythematosus (SLE) patients worldwide has consistently shown a correlation between high pollution levels and increased health complications. This includes more hospitalizations and disease activity in SLE patients, particularly in areas with poor air quality management practices.
The presence of harmful substances (i.e. particulate matter, nitrates, lead, carbon monoxide, and ozone) in the air pose health risks for SLE patients. Prolonged exposure to air pollution can trigger inflammation and oxidative stress, exacerbating conditions like SLE and impacting various organs.
Developing countries tend to have higher SLE incidence rates due to elevated gas and particle levels in the air, emphasizing the need for protective measures. Exposure to pollutants, such as PM2.5, PM10, SO₂, NO₂, and ozone, is associated with increased inflammatory markers and disease activity in SLE patients.
Overall, this research highlights the importance of monitoring and improving air quality to reduce the health risks and mortality rates associated with SLE, particularly in developing countries facing economic challenges in managing pollution levels.
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