A Case of Daptomycin-Induced Acute Eosinophilic Pneumonitis

Authors

  • Peter Iskander, MD The Wright Center for GME, Scranton, PA https://orcid.org/0000-0002-4437-7972
  • Aadhya Shenoy, MD The Wright Center for GME, Scranton, PA
  • Bhavika Gottipati, MD The Wright Center for GME, Scranton, PA
  • Natasha Khalid, MD The Wright Center for GME, Scranton, PA
  • Santosh Khanal, MD The Wright Center for GME, Scranton, PA
  • Shivangi Patel, MD The Wright Center for GME, Scranton, PA
  • Kavitha Singaravel The Wright Center for GME, Scranton, PA
  • Gary Decker MD Regional Hospital of Scranton, Scranton, PA
  • Milos Babic MD The Wright Center for GME, Scranton, PA

Keywords:

Daptomycin, Acute Eosinophilic Pneumoinitis

Abstract

Daptomycin is currently an FDA-approved treatment for various infections, whether they be blood or skin-related. One noted complication is the development of acute eosinophilic pneumonitis which can lead to worsening respiratory complications. Mainstay treatment is to discontinue the offending agent, administer steroids, and conservative management to target respiratory symptoms. We present a case of a patient experiencing increasing oxygen requirements, ultimately requiring intubation, after initiating Daptomycin for a prosthetic joint infection. The antibiotic was discontinued, he was treated with IV steroids and was eventually able to be weaned off the ventilator. Care should be taken when initiating such antibiotics in patients with compromised health. Vitals and respiratory status should be closely monitored and there should be a low threshold for discontinuing the medication should they worsen.

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Published

2024-06-30

How to Cite

Iskander, P., Shenoy, A., Gottipati, B., Khalid, N., Khanal, S., Patel, S., Singaravel, K., Decker, G., & Babic, M. (2024). A Case of Daptomycin-Induced Acute Eosinophilic Pneumonitis . The Scholarly Society of America, 3(1), 29–33. Retrieved from http://ssajm-online.org/ojs/index.php/SSAJM/article/view/25

Issue

Vol. 3 (2024): Issue 1

Section

Case Reports

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